Foot and Mouth Disease

Foot and Mouth Disease Author Francisco Sobrino
ISBN-10 0849329515
Release 2004-08-12
Pages 600
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The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptable diagnosis and control measures is essential to effectively combat this devastating virus. Foot and Mouth Disease: Current Perspectives benefits researchers by presenting the latest developments resulting from the upsurge in data concerning this disease. Interdisciplinary in its approach, this book offers the first coherent picture of emerging strategies for diagnosis and control. With contributions from respected FMD researchers worldwide, this volume provides comprehensive coverage of the entire spectrum of FMD issues. Topics include genome organization, translation and replication of FMD virus RNA, proteinases, virus particles, clinical signs of FMD, and much more. This book delivers essential information for everyone with an interest in FMD, such as virologists, molecular biologists, biotechnologists, veterinarians, and pharmaceutical and biotech researchers.

Foot and Mouth Disease Virus

Foot and Mouth Disease Virus Author Francisco Sobrino
ISBN-10 9781910190524
Release 2017-01-15
Pages 444
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Fifteen years after the devastating 2001 European foot-and-mouth disease (FMD) outbreak, the virus causing that shocking episode continues to pose a major threat to animal health worldwide. The development of more effective, sustainable and socially acceptable disease control measures remains a key task. This volume provides essential scientific background on FMD and its etiological agent, FMD virus, as well as comprehensive, interdisciplinary and up-to-date information on basic research findings and applied developments contributing to FMD control. The eighteen chapters have been written by leading FMD researchers. Topics include genome organization, translation and replication, virus-coded proteinases, structure of virus particles, cell receptors and host range, the RNA polymerase, quasispecies dynamics and virus evolution, innate and acquired immune responses, and the clinical signs of FMD and its natural habitats. Further chapters deal with various aspects of disease control such as diagnosis, current and new vaccines, antivirals and models of epidemiology. The role of international organizations in FMD control and the impact of FMDV as a re-emergent virus are also addressed. The book is required reading for everyone involved in FMD and is an important acquisition for all microbiology libraries.

Social and Behavioral Research for Homeland Security

Social and Behavioral Research for Homeland Security Author John G. Voeller
ISBN-10 9781118651803
Release 2014-01-16
Pages 85
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Social and Behavioral Research for Homeland Security features articles from the Wiley Handbook of Science and Technology for Homeland Security covering social and psychological aspects of terrorism and counterterrorism efforts from different perspectives. First, it examines the roots of terrorism; second, it explores the consequences of terrorism; then communication, training, and learning development of responders and the public in situations of terror attacks, are discussed.

Animal Viruses

Animal Viruses Author Thomas C. Mettenleiter
ISBN-10 9781904455226
Release 2008-01
Pages 531
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The study of animal viruses contributes to the general understanding of the molecular basis of viral infection. The emergence of the SARS (Severe Acute Respiratory Syndrome) virus in the human population, coming from an animal source, highlights the importance of animals in harboring infectious agents. In addition, it has been recognized recently that influenza viruses, which persist in their natural avian host, can directly infect humans. In this book, an international panel of leading virologists provide a state-of-the-art overview of the field, comprehensively detailing the current understanding of viruses, their replication, evolution, and interaction with the host. The authors emphasize strategic and methodological aspects of current research, and provide key related references. Topics include foot-and-mouth disease virus, Pestivirus, Arteriviridae, Coronaviruses (including SARS), Herpesviridae, Paramyxoviridae, influenza viruses, Reoviridae, porcine circoviruses, Asfarviridae and much more.

Influenza Virology

Influenza Virology Author Yoshihiro Kawaoka
ISBN-10 1904455069
Release 2006
Pages 367
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Three times in the last century, influenza viruses have undergone major genetic changes resulting in global pandemics that had devastating effects. The most infamous pandemic was the "Spanish Flu" which affected up to 25% of the world population and is thought to have killed at least 40 million people. In 1997 and 2003, a new influenza A virus of H5N1 subtype emerged in Asia and was transmitted directly from birds to humans with lethal outcomes. Despite monumental efforts to contain them, the H5N1 viruses expanded their territory and caused a major outbreak in wild waterfowl in China in 2005. Despite extensive, coordinated efforts by various agencies and disciplines, both national and international, we are ill-equipped for a new influenza pandemic. In fact, it is highly unlikely that adequate supplies of vaccine for the H5N1 viruses will be prepared prior to the occurrence of the next pandemic. To combat the outbreaks that will undoubtedly occur in the near future, a better understanding of influenza virus itself is urgently needed along with a greater knowledge of the virus-host interaction and mechanisms of drug resistance. In this timely book, world renown scientists - including the 1996 Nobel Prize winner, Peter Doherty - critically review the most important issues in this rapidly expanding field. Coverage includes analysis of influenza RNP, viral entry and intracellular transport, epidemiology, host range and pathogenicity, antivirals, vaccines, H5 viruses, and much more.


Cytomegaloviruses Author Matthias Johannes Reddehase
ISBN-10 1904455026
Release 2006-01
Pages 619
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Cytomegaloviruses are members of the herpesvirus group and can infect humans and other primates. Between 50-80% of adults in developed countries and up to 100% in developing countries are infected with human cytomegalovirus. Infection causes problems in immunocompromised hosts including AIDS victims or patients undergoing organ and stem cell transplantation and congenital infection can cause birth defects in the child. Development of an effective vaccine has high priority. In this book, leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology, and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenesis, virus entry and activation of innate immunity, regulation of viral gene expression, regulation of viral mRNA export, animal models of infection, novel therapeutics, vaccine development, antivirals, and much more.

Foodborne Pathogens

Foodborne Pathogens Author James L. Smith
ISBN-10 190445500X
Release 2005
Pages 453
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Foodborne pathogens continue to cause major public health problems worldwide. These organisms are the leading causes of illness and death in less developed countries, killing approximately 1.8 million people annually. In developed countries, foodborne pathogens are responsible for millions of cases of infectious gastrointestinal diseases each year, costing billions of dollars in medical care and lost productivity. In addition, new foodborne diseases are likely to emerge driven by factors such as pathogen evolution, changes in agricultural and food manufacturing practices, and changes to the human host status. A third problem is that there are growing concerns that terrorists could use pathogens to contaminate food and water supplies in attempts to incapacitate thousands of people and disrupt economic growth. Fuelled by these concerns, research into the genomics, molecular biology, and microbiology of the most important foodborne pathogens has escalated to unprecedented levels in recent years. Foodborne Pathogens represents a cutting edge summary of all the latest advances, providing a coherent picture of the current status of research. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter Infections, Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging Foodborne pathogens. The book is essential reading for microbiologists, food scientists, and particularly anyone involved in food safety.

Epstein Barr Virus

Epstein Barr Virus Author Erle S. Robertson
ISBN-10 1904455034
Release 2005
Pages 770
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Renowned EBV experts provide a critical and comprehensive review of every aspect of this important virus. By integrating genetic, immunologic, and cell biologic approaches to elucidate pathogenesis, new insights into the molecular and cellular interaction between EBV and its human host have emerged. Topics covered include: Discovery, history and seroepidemiology, EBV and the immune response, EBV genetics, EBV infection and persistence, latency, lytic proteins and reactivation control, vaccine approaches, animal models, and the future of EBV studies.

Papillomavirus Research

Papillomavirus Research Author M. Saveria Campo
ISBN-10 1904455042
Release 2006
Pages 423
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Papillomaviruses are oncogenic DNA tumor viruses that infect humans and animals. Human papillomavirus is one of the most common causes of sexually transmitted infection in the world and can also cause cancer. Papillomavirus research has been revolutionized in recent years with the advent of new technologies such as organotypic raft cultures, virus-like particles, and transgenic mice. New facets of virion structure, life cycle, immunology, and oncogenicity have recently emerged. In this timely book, leading scientists review current aspect of papillomavirus research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology, and vaccine development. Topics covered include epidemiology and taxonomy, phylogenetic analysis, gene expression, regulation of DNA replication, transcription factor proteins, organotypic raft cultures, virus-like particles, and much more. Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development.

The Microbe Host Interface in Respiratory Tract Infections

The Microbe Host Interface in Respiratory Tract Infections Author Jan L. L. Kimpen
ISBN-10 0849336465
Release 2004-12-22
Pages 324
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The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them. The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is divided into three sections: the first reviews topics of general interest; the second focuses on bacterial and atypical RTIs; while the final section covers viral RTIs. Each of the chapters is the work of two or more of the top scientists in the field writing about their own pioneering research. Various chapters comment on vaccines, antibiotics, and molecular diagnostic methods. This cutting-edge work is essential reading for research microbiologists and other scientists involved in the investigation and treatment of RTIs.


Mycoplasmas Author Alain Blanchard
ISBN-10 0849398614
Release 2005-06-06
Pages 600
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Created by leading international experts, Mycoplasmas: Molecular Biology, Pathogenicity, and Strategies for Control represents a cutting-edge summary of current knowledge in the field. Mycoplasmas, or mollicutes, form a large group of bacteria that can infect humans, animals, and plants. This comprehensive text focuses on the molecular and cell biology of mycoplasmas and related mollicutes. It also explores pathogenesis and emerging strategies for control. Coverage includes a variety of topics including genome analysis, gene vectors, genomics, motility, chemotaxis, attachment, molecular epidemiology, immunology, diagnosis, antimicrobial resistance, and vaccine technology.

The Picornaviruses

The Picornaviruses Author Ellie Ehrenfeld
ISBN-10 9781555816032
Release 2010-09-15
Pages 536
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A springboard for developing new approaches to understanding, preventing, and treating picornaviral diseases. • Examines the most current breakthroughs as well as the challenges that lie ahead in picornavirus research; encapsulates current knowledge of the molecular biology, evolution, and pathogenesis of this large family of viruses; and, examines the diseases that these viruses cause and the latest vaccines and antiviral drugs to prevent and control those diseases. • Explores the structural and mechanistic bases of picornavirus replication, highlighting new insights about the host cell interactions needed for virus growth; and, illustrates how the regular occurrence of mutations, typical of viruses with RNA as genetic material, generates the quasispecies dynamics that underlie viral fitness. • Focuses on picornaviruses that cause disease, examining pathogenicity and innate and acquired immune responses against infection as well as the latest vaccine and antiviral drug strategies.

Quasispecies Concept and Implications for Virology

Quasispecies  Concept and Implications for Virology Author Esteban Domingo
ISBN-10 9783540263975
Release 2006-02-19
Pages 410
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Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.

Silent Victories

Silent Victories Author John W. Ward
ISBN-10 9780195150698
Release 2007
Pages 484
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'Silent Victories' takes a unique approach in its exploration of ten major public health issues addressed in the 20th century: for each issue, leading scientists in the field trace the discoveries, practices and programs that reduced morbidity and mortality from disease and injury.

Conservation and Development Interventions at the Wildlife livestock Interface

Conservation and Development Interventions at the Wildlife livestock Interface Author Steven A. Osofsky
ISBN-10 2831708648
Release 2005
Pages 220
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During a forum held at the Vth IUCN World Parks Congress in South Africa in 2003, the Wildlife Conservation Society (WCS) and the IUCN SSC Veterinary and Southern Africa Sustainable Use Specialist Groups (VSG and SASUSG) brought together nearly 80 experts from Africa and beyond to develop ways to tackle the immense health-related conservation and development challenges at the wildlife/domestic animal/human interface facing East and Southern Africa today, and tomorrow. This volume focuses on several themes of critical importance to the future of animal agriculture, wildlife, and, of course, people: competition over grazing and water resources, disease mitigation, local and global food security and other potential sources of conflict related to the overall challenges of land-use planning and the pervasive reality of resource constraints. This publication seeks to draw attention to the need to move towards a ?one health” perspective ? an approach that was the foundation of the discussions in Durban, and a theme pervading these thought-provoking, insightful, and practical Proceedings.

Desk Encyclopedia Animal and Bacterial Virology

Desk Encyclopedia Animal and Bacterial Virology Author Brian W.J. Mahy
ISBN-10 0123751454
Release 2010-04-06
Pages 646
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This volume contains 81 chapters that relate to veterinary and bacterial virology. The first section describes general features of farm and other animals of agricultural importance. The following three sections detail other animal viruses, avian viruses, and viruses affecting aquatic species such as fish and crustaceans. The Section five deals with viruses which infect bacteria. The most comprehensive single-volume source providing an overview of virology issues related to animal and bateria Bridges the gap between basic undergraduate texts and specialized reviews Concise and general overviews of important topics within the field will help in preparation of lectures, writing reports, or drafting grant applications

The Spanish Influenza Pandemic of 1918 1919

The Spanish Influenza Pandemic of 1918 1919 Author Maria Porras-Gallo
ISBN-10 9781580464963
Release 2014-11-15
Pages 290
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Sheds new light on what the WHO described as "the single most devastating infectious disease outbreak ever recorded," focusing on social control, gender, class, religion, national identity, and military medicine's reactions to the pandemic.